Life Extension Cognitex Elite Pregnenolone 60 Vegetarian Tablets

What it is

Cognitex® Elite Pregnenolone is a Life Extension dietary supplement supplied as 60 vegetarian tablets in a dark blue bottle. The label sets a serving at two tablets, so one bottle covers 30 servings. Each serving delivers two minerals and seven further named compounds, among them 333 mg of SIBELIUS™: SAGE extract, 200 mg of a proprietary wildcrafted blueberry blend, 125 mg of Sensoril® ashwagandha extract and 50 mg of pregnenolone.

The bottle is manufactured for Quality Supplements and Vitamins, Inc. of Ft. Lauderdale, Florida. The front panel carries a gluten-free mark and a “NON GMO LE CERTIFIED” mark, and identifies the contents as 60 vegetarian tablets. It is stocked here alongside the rest of our Supplements range.

What’s inside

Every amount below is transcribed from the Supplement Facts panel on the bottle and is stated per two-tablet serving. Seven of the nine rows carry no percent Daily Value, because no Daily Value has been established for those compounds.

• Calcium 200 mg (15% DV) and phosphorus 160 mg (13% DV) — both supplied by a single compound, dicalcium phosphate, which is why the two rows share a source. Calcium is the mineral most abundant in the human body; the NIH Office of Dietary Supplements fact sheet on calcium gives general background on it.
• SIBELIUS™: SAGE extract (leaf), 333 mg — the largest single amount on the panel, standardized to 2.5% rosmarinic acid. Sage is a woody garden herb in the mint family, as familiar in cooking as in supplement formulas; rosmarinic acid is a plant polyphenol that also occurs in rosemary and lemon balm. SIBELIUS is a trademark of Sibelius Limited.
• Proprietary Wildcrafted Blueberry Blend, 200 mg — blueberry fruit extract drawn from six named Vaccinium species: V. angustifolium, V. corymbosum, V. alaskaense How., V. ovalifolium Sm., V. uliginosum L. and V. cespitosum Michx. “Wildcrafted” means harvested from wild stands rather than grown in cultivated rows. This row is a proprietary blend, so the panel prints one 200 mg total and no individual figure for any species. The NIH background page on botanical dietary supplements explains how plant extracts like these are prepared and standardized.
• Sensoril® ashwagandha extract (root, leaf), 125 mg — standardized to 10% withanolide glycoside conjugates. Ashwagandha is a shrub, Withania somnifera, with a long history in Ayurvedic preparations in India; the NCCIH page on ashwagandha covers what is and is not known about it. Sensoril is a registered trademark of Natreon, Inc., protected under US Patent Nos. 6,153,198 and 6,173,092. Note that this extract is drawn from both root and leaf, which not every ashwagandha ingredient is.
• Phosphatidylserine, 100 mg — a phospholipid, one of the class of fat molecules that make up the outer membrane of cells. It occurs in ordinary foods including soy lecithin.
• Pregnenolone, 50 mg — the compound the product is named for. It is a steroid molecule that the human body makes from cholesterol, and it sits near the start of the body’s own chain of steroid synthesis.
• Uridine-5’-Monophosphate, disodium, 50 mg — a nucleotide, one of the molecular building blocks from which RNA is assembled, supplied here as its disodium salt.
• Vinpocetine, 20 mg — the smallest amount on the panel. Vinpocetine is derived from vincamine, a compound found in the lesser periwinkle plant, Vinca minor.

The tablets are held together and coated with the following, listed on the panel as other ingredients: microcrystalline cellulose, stearic acid, calcium silicate, croscarmellose sodium, silica, an aqueous film coating of hypromellose, glycerin and purified water, maltodextrin, and vegetable stearate. There is no gelatin in that list, which is consistent with the vegetarian tablet stated on the front of the bottle.

Supplement Facts

How to use it

A serving is two vegetarian tablets, and the bottle holds 30 of them. The tablets carry an aqueous film coating, listed on the panel as hypromellose, glycerin and purified water.

Follow the directions printed on the bottle label itself, and do not take more than the serving stated there. If you already take a separate ashwagandha, phosphatidylserine or blueberry extract product, read both labels side by side before combining them, so that you know what the total daily amount of each compound comes to.

Who it’s for

This is a product for adults 18 and over who prefer one multi-ingredient tablet over several single-ingredient bottles. The nine-row panel covers ground that would otherwise take four or five separate purchases — a sage extract, a blueberry extract, an ashwagandha extract, phosphatidylserine and pregnenolone — which is the practical argument for a formula of this kind.

It suits vegetarians, since the tablets are stated as vegetarian on the front panel and the other-ingredients list contains no gelatin. It also suits shoppers avoiding gluten, as the front of the bottle carries a gluten-free mark. At 30 servings a bottle, it is sized for someone buying a steady supply rather than trying a single dose. You will find comparable multi-ingredient formulas in our Supplements category.

Good to know

This is a dietary supplement, not a medicine, and it is intended for adults 18 and over. Speak to a licensed healthcare professional before starting it — particularly if you are pregnant or nursing, are managing a health condition, or take prescription medication. The NCCIH overview of dietary and herbal supplements is a useful general starting point on how supplements are regulated and what questions to ask.

Two practical points from the panel. First, the blueberry row is a proprietary blend, so the 200 mg figure is the total for all six species together and no per-species amount is published. Second, seven of the nine rows are marked with a double asterisk, meaning no Daily Value has been established for those compounds — only the calcium and phosphorus rows can be read as a percentage of a daily reference amount.

The back panel also prints a toll-free number for reporting adverse events, alongside the trademark and patent attributions for the SIBELIUS and Sensoril ingredients. Keep the bottle out of reach of children.

Frequently Asked Questions

How many tablets are in a bottle, and how many servings is that?

There are 60 vegetarian tablets in the bottle, which is 30 servings. The Supplement Facts panel sets a serving at two tablets, and 60 tablets divided by two gives the 30 servings printed on the label.

Are the tablets vegetarian and gluten-free?

Yes to both, according to the bottle. The front panel states “60 Vegetarian Tablets” and carries a gluten-free mark, and the other-ingredients list on the back contains no gelatin and no wheat-derived ingredient.

What is Sensoril ashwagandha, and how much is in a serving?

Sensoril is a branded ashwagandha extract, and there is 125 mg of it per two-tablet serving. It is drawn from both the root and the leaf of Withania somnifera and standardized to 10% withanolide glycoside conjugates.

Does the panel give an amount for each blueberry species?

No — it gives a single 200 mg total for the blend as a whole. The label names six Vaccinium species in the blend but, because it is declared as a proprietary blend, the individual amounts are not disclosed and cannot be quoted here.

How is the order packaged for delivery?

Orders ship in plain outer packaging with no product imagery and no brand marks on the outside. It will not show the Gear Isle name, and nothing on the exterior describes what is inside.

Product information compiled and reviewed by the Gear Isle product team. We transcribe supplement facts directly from manufacturer packaging. Found an error? Tell us.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Dietary supplement for adults 18 and over. Consult a licensed healthcare professional before use, especially if you have a medical condition, heart concerns, or take prescription medication (including nitrates). Keep out of reach of children.